B. Hu, Z. R. Zheng et al., “Preliminary study on the DNA barcoding in Dendrobium officinale germplasm resources,”, X. M. Chen, C. L. Wang, J. S. Yang, and S. X. Guo, “Research progress on chemical composition and chemical analysis of Dendrobium officinale,”, Z. C. Zhang, J. Please enable it to take advantage of the complete set of features! 2020-06-02 | 0 Comment. Dendrobii Officinalis Caulis, the stems ofDendrobium officinale Kimura et Migo, as a tonic herb in Chinese materia medica and health food in folk, has been utilized for the treatment of yin-deficiency diseases for decades.Methods. Reference page. >, United States > Missouri > Saint Louis City. The appearance of Dendrobium officinale and other species of Dendrobium is very similar, especially after processing into “tiepifengdou”; it is difficult to distinguish them through morphological identification [93]. Evidence-Based Complementary and Alternative Medicine, Mar 2017 Research showed that O-acetyl-glucomannan, Dendronan® (Figure 2, A), from Dendrobium officinale [34] has been isolated and was affirmed immunomodulatory activity in vitro [35] and in vivo [36], as well as improvement in colonic health of mice [37]. This may mainly attribute to the major and bioactive components: polysaccharides. Dendrobium officinale caulis is the dried mature stems (Mat) of D. officinale Kimura et Migo. C. G. Cai, W. D. Zhang, and M. R. Zhang, One kind of hypoglycemic and hypolipidemic Dendrobium officinale compounds and its preparation method, China Patent CN104126746A, 2014. Omeprazole (B1702400) was bought from Madaus GmbH (Beijing, China). The stems of Dendrobium officinale are mainly used as health food in folk. IC50 of P388 murine leukemia cell treated by erianin in MTT assay was 0.11 μM [40]. The present study aimed to explore the cardioprotective potential of the water extract of Dendrobium officinale Kimura et Migo (DOE) on myocardial ischemia in mice. 2012R10044-03). Alibaba offers 24 Dendrobium Officinale Kimura Et Migo Suppliers, and Dendrobium Officinale Kimura Et Migo Manufacturers, Distributors, Factories, Companies. Its wide modern pharmacological actions in hepatoprotective effect, anticancer effect, hypoglycemic effect, antifatigue effect, gastric ulcer protective effect, and so on were reported. Ming Zhao, Jungang Han. BACKGROUND Emerging evidence suggests the potential of Dendrobium officinale Kimura et Migo (DO) in treating the complications of diabetes mellitus (DM). In addition, amounts of polysaccharide were greater in biennial Dendrobium officinale than annual or triennial ones [29], while the wild type contained more content compared to the cultivated type [30]. Pesticides are inevitably applied on D. officinale in commercial artificial-sheltered cultivation, yet little is known about pesticide residue levels in D. officinale. Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a functional food and medicine herbal, has shown great pharmacological activity on diabetes and hypertension. Copyright © 2017 Hanxiao Tang et al. Methods. Since there are lipids, proteins, pigments, and other impurities after the process of separation of polysaccharides, other separation methods, such as ion-exchange chromatography, gel filtration chromatography, and HPLC, are needed to purify the crude polysaccharides [24]. However, polysaccharides are acknowledged as complex biological macromolecules; the ways and sequences of connections of the monosaccharides determine the difficulty of polysaccharides’ analyses [25]. Therefore, the identification of Dendrobium officinale is more precise due to the gene technology, but genetic fingerprints are difficult to evaluate the quality, so the gene technology combining with the physical and chemical identification is necessary. Actually, different production origins, processing methods, growing years, and cultivated or wild and different parts of Dendrobium officinale are all related to polysaccharide content. Research showed that low-grade fever after gastric cancer operations, atrophic gastritis, mouth ulcers, and diabetes were treated by the fresh Dendrobium officinale in TCM [19]. Rapid propagation technology has gradually matured, so yield is no longer the bottleneck of Dendrobium officinale development. Z. H. He and X. P. He, “One kind of immuno-enhancement Dendrobium officinale health products,” China Patent CN103816389A, 2014. [9]; however this Latin name was later disputed and considered the synonym of Dendrobium moniliforme (L.) Sw. [10, 11]. Previous studies suggest that these different plant parts possess similar pharmacological activities. This site needs JavaScript to work properly. Evid Based Complement Alternat Med. 2020 Feb;40(1):35-47. doi: 10.1007/s11596-020-2144-x. Among these compounds, 17 bibenzyls named Dendrocandins A–Q (14–30) (Figure 2) were extracted by Li et al. In addition, ALT, AST, and TC of Dendrobium officinale treated mice models with chronic alcoholic liver injury were elevated compared to the normal groups [65]. Dendrobium officinale exhibited a significant hypoglycemic effect in adrenaline hyperglycemia mice and streptozotocin-diabetic (STZ-DM) rats [71]. Response of Dendrobium officinale Kimura et Migo, a Prized Medicinal Plant, to Continuous UV-B Irradiation at Different C/N Ratios. The fine powder solution of Dendrobium officinale (1.5, 3 g/kg) can reduce the levels of TG, TCHOL, and LDL-C in serum significantly and reduce the expression of TNF-α and IL-6 in ApoE−/− mice. In addition, it could reduce areas of atheromatous plaque in aortic valve and arch in ApoE−/− mice and then decrease the expression of TNF-α and IL-6 in aortic arch [77]. Abstract: Dendrobium officinaleKimura et Migo is a commercially and pharmacologically highly prized species widely used in Western Asian countries. The functions and indications of tiepishihu and shihu are quite similar in traditional Chinese medicine (TCM) [17, 18]. Research showed that Dendrobium officinale polysaccharides (DOP) accelerated the metabolism of serum TG and TC, while increased liver ADH and ALDH activities, which recovered disorders of lipid metabolism and accelerated excretion of alcohol and its metabolites [64]. Dendrobium officinale Kimura et Migo is a commercially and pharmacologically highly prized species widely used in Western Asian countries. Our results showed that Streptozotocin-induced diabetic model was effectively achieved and serum CK and LDH levels were significantly increased in mice with diabetic cardiomyopathy. After the successful establishment of the irritable gastric ulcer model (induced by cold water immersion) and chemical gastric ulcer model (indometacin-induced, 40 mg/kg, gavage) the ulcer index was calculated by Guth standard scoring method. As reported, the combination of Dendrobium officinale and American Ginseng could strengthen cell-mediated immunity, humoral immunity, and monocyte-macrophages functions of mice [16]. Furthermore, the 15% decoction of Dendrobium officinale was used for mice sperm malformation test, Ames test, and micronucleus test of bone marrow in mice, and all test results were negative. Z. Chen, “Extraction, isolation and analysis of Dendrobium officinale's polysaccharides,”, H. Yu, Y. Qu, and S. Chen, “Efficacy of Golden Dendrobium tablets on clearing and smoothing laryngopharynx,”, H. Xu, Z. Wang, X. Ding, K. Zhou, and L. Xu, “Differentiation of Dendrobium species used as “Huangcao Shihu” by rDNA ITS sequence analysis,”, Y. Lam, T. B. Ng, R. M. Yao et al., “Evaluation of chemical constituents and important mechanism of pharmacological biology in, J. Xu, W. M. Zhao, Z. M. Qian, J. Guan, and S. P. Li, “Fast determination of five components of coumarin, alkaloids and bibenzyls in Dendrobium spp. 2020 Feb 28;8:153. doi: 10.3389/fbioe.2020.00153. In recent years, the development of Dendrobium officinale health care products is promising [15]. Curr Med Sci. This concentration (200 mg/kg) had the strongest inhibitory effect of gastric injury (76.6% inhibition of gastric injury rate) [75]. Therefore, accurate determination of polysaccharide content is of great significance. The response of Dendrobium officinale Kimura et Migo (D. officinale) to continuous UV-B irradiation at different carbon to nitrogen ratios (C/N ratios) was investigated. Further, DOP ameliorated the abnormalities of aquaporin-5 (AQP-5) that was supported by in vitro study on A-253 cell line and maintained its function of saliva secretion [79]. Dendrobii Officinalis Caulis, the stems of Dendrobium officinale Kimura et Migo, as a tonic herb in Chinese materia medica and health food in folk, has been utilized for the treatment of yin-deficiency diseases for decades. Therefore, further methods to explore the advanced structures and structure-activity relationships of Dendrobium officinale polysaccharides need to be established. Epub 2012 Nov 29. Hypoglycemic activity, another important property of Dendrobium officinale, has been studied a lot. Dendrobium Officinale Kimura et Migo Ameliorates Insulin Resistance in Rats with Diabetic Nephropathy. Consequently, the following points deserve further investigation. Dendrobium officinale containing a high content of (E)-2-hexenal (106) shows bactericidal activity against Pseudococcus viburni, Pseudococcus affinis, Bemisia sp., and Frankliniella occidentalis [46]. There are 74 species and 2 variants of genus Dendrobium Sw. in China [7]. Information for analysis ofDendrobium officinale Kimura et Migo was obtained from libraries and Internet scientific databases such as PubMed, Web of Science, Google Scholar, ScienceDirect, Wiley InterScience, Ingenta, Embase, CNKI, and PubChe… Limonene contains anticancer properties with effects on multiple cellular targets in preclinical models [45]. Besides, compared to the model group of mice with acute alcoholic hepatic injury, fresh Dendrobium officinale and tiepifengdou groups could increase the SOD and reduce MDA of serum and liver tissue [66]. 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